How the power players do it - by Fortune senior editor at large Patricia Sellers

Handler and Huffington on managing stress and life

January 12, 2012: 11:23 AM ET

Chelsea Handler showed us a new side of her media brand-ness last night on the premiere of the NBC (CMCSA) sitcom Are You There, Chelsea? The standup comic/late-night TV host/best-selling author/rising-star entrepreneur plays main character Chelsea's pregnant and proper sister on the show.

Let's be clear, this is not Handler's fantasy life. At the Fortune Most Powerful Women Summit in October, Arianna Huffington tried her best to convince Handler of the joys of motherhood. (Huffington, who heads the AOL (AOL) Huffington Post Media Group, has two daughters.)  Handler, who seems focused on conquering the media universe, had zero interest. Still, these two MPW, who had never met before the Summit, hit it off and turned out to share plenty in common. Here are Handler and Huffington on mothers, meditation and managing stress:

Click here for the full transcript of Handler and Huffington's conversation at the 2011 MPW Summit.

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